Cellular content of amniotic fluid as predictor of central nervous system malformations.

Abstract
Prospective observations on 442 consecutive samples have confirmed that [human] pregnancies with CNS malformations are regularly associated with an abnormal cellular content of amniotic fluid. A crude semiquantitative test of the cell content can give valuable clinical information in relation to borderline amniotic fluid alpha-fetoprotein [AFP] values and help to detect false positive AFP.