Oncolytic viral therapy for human colorectal cancer and liver metastases using a multi‐mutated herpes simplex virus type‐1 (G207)
- 1 August 1999
- journal article
- Published by Wiley in The FASEB Journal
- Vol. 13 (11) , 1325-1334
- https://doi.org/10.1096/fasebj.13.11.1325
Abstract
G207 is a multi-mutated, replication-competent type-1 herpes simplex virus designed to target, infect, and lyse neurological tumors. This study examines the feasibility of using G207 in the treatme...Keywords
Funding Information
- U.S. Public Health Service (T32 CA 09501, T32 CA 09685)
- National Institutes of Health (CA 76416, CA 72632)
This publication has 34 references indexed in Scilit:
- Treatment of Human Breast Cancer in a Brain Metastatic Model by G207, a Replication-Competent Multimutated Herpes Simplex Virus 1Human Gene Therapy, 1998
- Herpes Simplex VirusesClinical Infectious Diseases, 1998
- Enhancement of replication of genetically engineered herpes simplex viruses by ionizing radiation: a new paradigm for destruction of therapeutically intractable tumorsGene Therapy, 1998
- Cancer statistics, 1998CA: A Cancer Journal for Clinicians, 1998
- Prevention of hepatic tumor metastases in rats with herpes viral vaccines and gamma-interferon.Journal of Clinical Investigation, 1997
- Rapid Production of Interleukin-2-Secreting Tumor Cells by Herpes Simplex Virus-Mediated Gene Transfer: Implications for Autologous Vaccine ProductionHuman Gene Therapy, 1996
- Enhancement of Gene Therapy Specificity for Diffuse Colon Carcinoma Liver Metastases with Recombinant Herpes Simplex VirusAnnals of Surgery, 1996
- Dormant liver metastases: an experimental studyBritish Journal of Surgery, 1992
- In Vivo Behavior of Genetically Engineered Herpes Simplex Viruses R7017 and R7020: Construction and Evaluation in RodentsThe Journal of Infectious Diseases, 1988
- Failure Patterns Following Curative Resection of Colonic CarcinomaAnnals of Surgery, 1984