Renin Angiotensin Involvement in Transient Hypertension After Renal Injury

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Abstract
Transient hypertension occurred in 3 patients shortly after blunt injury to the abdomen. Renal trauma was suspected in all 3 patients, and radiological evidence for renal injury was present in 2. Plasma renin activity definitely was elevated in 1 patient and probably was elevated in another. There was a decrease in blood pressure in all 3 patients during infusion of the angiotensin II analogue.sbd.saralasin.sbd.showing that the hypertension in these patients was angiotensin-mediated. Renal function as reflected by the blood urea nitrogen, creatinine and electrolytes was not impaired significantly. Acute hypertension after blunt abdominal trauma may be angiotensinogenic and is not necessarily sustained.

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