The Rh System

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Abstract
A consanguineous ♂R1R2 × ♀R1R1 mating is reported which produced one child, four R1R1 and two R1R2 children. Nonpaternity and nonmaternity are ruled out as an explanation for the anomalous phenotype. The authors produce evidence indicating that this is indistinquishable from heritable and deduce from that it is, therefore, identical with that gene. Three explanations are offered for its occurrence here and two discarded. The third is a mutation: they favor the hypothesis that in this they are seeing the expression of a ‘gene of control’ and its effect on a ‘gene of structure’ in the complex that is Rh.
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