In Vitro Antifungal Activities of the New Triazole UR-9825 against Clinically Important Filamentous Fungi
Open Access
- 1 September 2001
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 45 (9) , 2635-2637
- https://doi.org/10.1128/aac.45.9.2635-2637.2001
Abstract
We used a modified reference microdilution method (the M-38P method) to evaluate the in vitro activities of the new triazole UR-9825 in comparison with those of amphotericin B against 77 strains of opportunistic filamentous fungi. UR-9825 was clearly more active than amphotericin B against all fungi except Fusarium solani and Scytalidium spp. Notably, UR-9825 had low MICs for Aspergillus fumigatus and Paecilomyces lilacinus (MICs at which 90% of isolates are inhibited, 0.125 μg/ml for both species).Keywords
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