Sub‐miniature end‐plate potentials at untreated frog neuromuscular junctions.

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Abstract
Some properties of unusually small spontaneous miniature end-plate potentials (sub-min EPP) at untreated end-plates of adult frogs [Rana temporaria and R. esculenta] was examined. These small potentials, which show a fast time course, add a highly skewed component to the normal Gaussian distribution of min EPP amplitudes. Sub-min EPP were not evoked by single nerve stimuli, though their frequency could be raised by tetanic nerve stimulation. When min EPP rate was raised by addition of La3+, sub-min EPP frequency was also increased, though by a smaller factor than normal min EPP. Sub-min EPP frequency was unchanged when min EPP rates were raised by either ethanol or hypertonic solutions.