bla CTX-M-2 Is Located in an Unusual Class 1 Integron (In35) Which Includes Orf513
Open Access
- 1 July 2002
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 46 (7) , 2303-2306
- https://doi.org/10.1128/aac.46.7.2303-2306.2002
Abstract
Examination of the bla CTX-M-2 gene in plasmid pMAR-12 by sequencing and PCR analysis revealed that the bla gene and the surrounding DNA, which is closely related (99% homology) to the Kluyvera ascorbata chromosomal DNA that contains the bla KLUA-1 gene, are located in a complex sul1 -type integron, termed In35, that includes Orf513. It is possible that bla CTX-M-2 was acquired by plasmid pMAR-12 through an uncharacterized recombinational event in which Orf513 could be involved.Keywords
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