Production of Ulcerated Atherosclerotic Lesions in Cockerels

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Abstract
1. Ulcerated abdominal aorta and coronary lesions have been produced in cockerels. 2. The prerequisite for ulceration is a lesion previously induced by a high-cholesterol, high-fat, low-protein diet, followed by the administration of large doses of estrogens. 3. The possible mechanisms leading to ulceration have been discussed.