Lipase-Catalyzed Enantioselective Acylation in the Ionic Liquid Solvent System: Reaction of Enzyme Anchored to the Solvent
- 1 March 2001
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 30 (3) , 262-263
- https://doi.org/10.1246/cl.2001.262
Abstract
The lipase-catalyzed enantioselective acylation of allylic alcohols in an ionic liquid solvent was demonstrated; the reaction was significantly dependent on the counter anion of the imidazolium salt and good results were obtained when the reaction was carried out in [bmim]PF6 or [bmim]BF4 as solvent. We also first demonstrated that it was possible to repeatedly use the enzyme in the ionic liquid solvent system.Keywords
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