Aryl Hydrocarbon Hydroxylase Induction in Rat Tissues by Naturally Occurring Indoles of Cruciferous Plants2

Abstract
A phytochemical investigation to identify inducers of increased aryl hydrocarbon hydroxylase (AHH) activity from three cruciferous vegetables, Brussels sprouts, cabbage, and cauliflower, resulted in the identification of indole-3-acetonitrile, indole-3-carbinol, and 3,3′diindolylmethane as naturally occurring inducers. These compounds are produced during the hydrolysis of indolylmethyl glucosinolate by the plant enzyme myrosinase.

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