On the Specificity of Antibodies
- 17 January 1975
- journal article
- review article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 187 (4172) , 130-137
- https://doi.org/10.1126/science.46122
Abstract
When the ascitic forms of two antigenically distinct guinea pig hepatomas induced by diethylnitrosamine are treated in vitro with chemotherapeutic drugs, their sensitivity to killing by xenogeneic antibody plus guinea pig complement increases. The effect is dependent on drug dose, is reversible, and does not appear to be due to increased antigen expression or fixation of the early acting components of guinea pig complement.Keywords
This publication has 29 references indexed in Scilit:
- Binding of ϵ-DNP-L-lysine exceeding two moles by purified chicken IgG anti-DNP antibodyImmunochemistry, 1974
- THE STRANGE CROSS-REACTION OF MENADIONE (VITAMIN K3) AND 2,4-DINITROPHENYL LIGANDS WITH A MYELOMA PROTEIN AND SOME CONVENTIONAL ANTIBODIESThe Journal of Experimental Medicine, 1974
- Complex and polyfunctional antibodiesImmunochemistry, 1974
- Quantitative immunoligical studies on single amino acid substitution in human hemoglobin: Demonstration of specific antibodies toImmunochemistry, 1974
- CROSS-STIMULATION OF MONOCLONAL ANTIBODIES IN ANAMNESTIC RESPONSESThe Journal of Experimental Medicine, 1973
- Failure of Limiting Antigen Doses to Selectively Stimulate High-Avidity Memory CellsScience, 1973
- Speculations how specific are antibodies?Immunochemistry, 1973
- Hydrophobic binding sites on immunoglobulinsBiochemistry, 1970
- Relation between antigenic complexity and heterogeneity in the antibody responseBiochemistry, 1969
- The serological specificity of the poly-alanine immune systemImmunochemistry, 1964