A Convenient Synthesis of 3-Methylthiobenzaldehyde
- 1 January 1981
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 11 (10) , 849-851
- https://doi.org/10.1080/00397918108065665
Abstract
Requiring the title compound as a starting material, we were surprised to find only one published synthesis,1 involving five steps with an overall yield of 15%. This is in contrast to the 2-and 4-alkylthiobenzaldehydes, which may be synthesised in one step by reaction of sodium alkanethiolates with the readily available halobenzaldehydes2. 3-Halobenzaldehydes, although readily available, do not react under these conditions2.Keywords
This publication has 2 references indexed in Scilit:
- Catalytic Activities of Salicylaldehyde Derivatives. VI. Syntheses of Some Dimethylsulfonio Derivatives of SalicylaldehydeBulletin of the Chemical Society of Japan, 1978
- 536. Mechanism of aromatic side-chain reactions, with special reference to the polar effects of substituents. Part XV. Mesomeric effects of elements of the oxygen groupJournal of the Chemical Society, 1952