Rak Functions as a Tumor Suppressor by Regulating PTEN Protein Stability and Function

This publication has 24 references indexed in Scilit:

• Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery
  Nature Reviews Drug Discovery, 2005
• The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region
  Proceedings of the National Academy of Sciences, 1999
• New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
  Proceedings of the National Academy of Sciences, 1999
• Identification and characterization of a new oncogene derived from the regulatory subunit of phosphoinositide 3-kinase
  The EMBO Journal, 1998
• Transformation of Chicken Cells by the Gene Encoding the Catalytic Subunit of PI 3-Kinase
  Science, 1997
• TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta.
  1997
• Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
  Nature Genetics, 1997
• PTEN , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer
  Science, 1997
• Rak, a novel nuclear tyrosine kinase expressed in epithelial cells.
  1994
• A Retroviral Oncogene, akt , Encoding a Serine-Threonine Kinase Containing an SH2-Like Region
  Science, 1991