Direct Cerebrovasodilatory Effects of Halothane, Isoflurane, and Desflurane during Propofol-induced Isoelectric Electroencephalogram in Humans

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Abstract
Background: The effect of volatile anesthetics on cerebral blood flow depends on the balance between the agent's direct vasodilatory action and the indirect vasoconstrictive action mediated by flow-metabolism coupling. To compare the intrinsic action of volatile anesthetics, the effect of halothane, isoflurane, and desflurane on flow velocity in the middle cerebral artery during propofol-induced isoelectricity of the electroencephalogram was examined.