Synthesis of α-Amino Acids by Reaction oft-ButylN-(t-Butoxycarbonyl)iminoacetate WithC-Nucleophiles
- 1 January 1987
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1987 (03) , 223-225
- https://doi.org/10.1055/s-1987-27895
Abstract
The reaction of t-butyl N-(t-butoxycarbonyl)iminoacetate with Grignard reagents or enamines yields N-(t-butoxycarbonyl)amino acid t-butyl esters which can be easily converted into the free amino acids by treatment with acids.Keywords
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