Abstract
It is well known that with the grosser lesions of many of the ductless glands there are profound alterations in the subject's mental powers. There are doubtless many less pronounced mental alterations due to slighter lesions of these glands which are for the most part unrecog nised—in fact difference in character and disposition in different individuals and in the same individual at different times may be due to the variation in the balance of the internal secretions.

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