Loss of Neurons in Magnocellular and Parvocellular Layers of the Lateral Geniculate Nucleus in Glaucoma
Open Access
- 1 March 2000
- journal article
- laboratory sciences
- Published by American Medical Association (AMA) in Archives of Ophthalmology (1950)
- Vol. 118 (3) , 378-384
- https://doi.org/10.1001/archopht.118.3.378
Abstract
FOLLOWING the loss of afferent fibers in the central nervous system, target neurons are known first to become atrophic and then die by the process of transneuronal degeneration.1-3 In neurodegenerative diseases and brain trauma, the primary injury triggers transneuronal degeneration; this causes extension of the disease process to neurons relatively spared during the primary injury.4-6 Little information exists regarding neuronal changes in target central visual neurons following the loss of afferent optic nerve fibers in glaucoma.Keywords
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