Biochemical Characterisation of A Blood Group Activity on Human Platelets
- 1 August 1985
- journal article
- research article
- Published by Wiley in Vox Sanguinis
- Vol. 49 (2) , 149-153
- https://doi.org/10.1111/j.1423-0410.1985.tb00783.x
Abstract
A butanol extraction procedure was used to isolate the blood group A antigen determinants from platelet membranes and to determine their biochemical structure, glycolipid and/or glycoprotein. The blood group A serological activity resided entirely in the butanol (organic) fraction. When this fraction was analyzed by TLC, the A-inhibitory activity comigrated with extracts of erythrocyte type Aa, Ab and Ac variant structures. The ABO blood group A determinants on human platelets are glycolipid, similar in structure to glycolipid A determinants on erythrocytes.This publication has 4 references indexed in Scilit:
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