Development of Visual Centers in the Primate Brain Depends on Binocular Competition Before Birth
- 20 November 1981
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 214 (4523) , 928-931
- https://doi.org/10.1126/science.7302569
Abstract
Removal of 1 [Macaca mulatta] eye before birth permanently changes the cellular organization and synaptic connectivity of visual centers in the primate brain. Notable alterations occur. The lateral geniculate nucleus develops only 2 cellular layers and 1 interlaminar fiber band instead of the normal 6 layers and 5 bands. Aberrant synaptic connections are formed between the intact eye and the geniculate neurons that have lost their normal input. Ocular dominance columns fail to develop in the visual cortex.This publication has 18 references indexed in Scilit:
- Terminal Arbors of Axons That Have Formed Abnormal ConnectionsScience, 1978
- Genesis of the dorsal lateral geniculate nucleus in the rhesus monkey: Site and time of origin, kinetics of proliferation, routes of migration and pattern of distribution of neuronsJournal of Comparative Neurology, 1977
- Ferrier lecture - Functional architecture of macaque monkey visual cortexProceedings of the Royal Society of London. B. Biological Sciences, 1977
- Prenatal development of the visual system in rhesus monkeyPhilosophical Transactions of the Royal Society of London. B, Biological Sciences, 1977
- Prenatal genesis of connections subserving ocular dominance in the rhesus monkeyNature, 1976
- Neurons in Rhesus Monkey Visual Cortex: Systematic Relation between Time of Origin and Eventual DispositionScience, 1974
- Quantitative studies of transneuronal atrophy in the dorsal lateral geniculate nucleus of cats and kittensJournal of Comparative Neurology, 1973
- Modified Optic Projections after Unilateral Eye Removal in Young RatsBrain, Behavior and Evolution, 1973
- Laminar and columnar distribution of geniculo‐cortical fibers in the macaque monkeyJournal of Comparative Neurology, 1972
- Some Principles of Organization in the Dorsal Lateral Geniculate Nucleus; pp. 253–267Brain, Behavior and Evolution, 1972