Therapeutic management of extrahepatic manifestations in patients with chronic hepatitis C virus infection

Abstract
The hepatitis C virus (HCV) is a linear, single‐stranded RNA virus of the Flaviviridae family that was identified in 1989 and is recognized as the major causal agent of non‐A, non‐B hepatitis [1]. HCV infection is emerging as an extremely common and insidiously progressive liver disease that is often associated with extrahepatic manifestations, including autoimmune disorders. The clinical relevance of these phenomena is extremely variable, ranging from subclinical features or laboratory abnormalities to overt clinical manifestations that may be severe in some patients.

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