Does Adjuvant Therapy Work in Colon Cancer?

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Abstract
Colorectal carcinoma is second only to lung cancer as a cause of death from cancer in the United States. Although the majority of patients found to have a large-bowel tumor successfully undergo a removal of all gross tumor, 40 to 50 percent are found at the time of surgery to have invasion of the tumor through the serosa (Stage B2) or spread to regional lymph nodes (Stage C). The prognosis after such "complete" resection is closely related to surgical stage. The prognosis for each stage appears to have improved somewhat in recent years, most likely because of more . . .