Synthesis of oligonucleotides containing the oxidatively modified B site: unique binding affinity to the NF B p50 homodimer
Open Access
- 1 November 1999
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Symposium Series
- Vol. 42 (1) , 33-34
- https://doi.org/10.1093/nass/42.1.33
Abstract
Synthesis of oligonucleotide 26-mers including single 5-formyl-2′-deoxy-uridine (1) or 5-formyl-2′-O-methyl-uridine (2) in place of thymidine at the κB site has been accomplished. One of the 26-mers with 1 was critically discriminated by the NFκB p50 homodimer in binding.Keywords
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