BIPOLAR COURSE IN SCHIZO-AFFECTIVE ILLNESS

  • 1 January 1976
    • journal article
    • research article
    • Vol. 11  (2) , 195-204
Abstract
A chart review was done to examine the use of the diagnosis of schizophrenia, schizo-affective type, in clinical practice. Of 27 patients given this diagnosis over as 3-yr period, 13 had evidence of bipolar course in their illnesses. For the bipolar and unipolar groups, the most striking findings in 1st-degree relatives was the prominence of affective conditions. The bipolar group had a statistically significant earlier age for 1st psychiatric treatment and previous number of hospitalizations. Symptoms noted on admission were mostly affective, and the schizophrenic symptoms reported were considered overinclusive or unreliable by many clinicians. Both groups received treatment with antipsychotic and antidepressant medication. Six of 13 bipolar patients and no unipolar patients were treated with lithium carbonate. Five bipolar patients met research critiera of Feighner et al (1972) for primary affective illness and another met the criteria for schizophreniform illness. One unipolar patient met criteria for probable primary affective illness and another met the criteria for probable schizophreniform illness. The diagnosis of schizo-affective illness, as used in day to day clinical practice, does not identify a group of schizophrenic patients nor a homogeneous patient group. When affective schizophrenic features appear in a patient with a bipolar illness, the diagnosis of manic-depressive illness, not schizophrenia, should be given 1st consideration.