Clara Cell Proteins
- 1 December 2000
- journal article
- Published by Wiley in Annals of the New York Academy of Sciences
- Vol. 923 (1) , 43-58
- https://doi.org/10.1111/j.1749-6632.2000.tb05518.x
Abstract
Abstract: Clara cells are nonciliated, nonmucous, secretory cells of the pulmonary airways. These cells are known to secrete a variety of proteins, including Clara cell 10‐kDa protein/uteroglobin. This protein consists of a homodimer of 70–77 amino acid polypeptides arranged in antiparallel fashion. In vitro testing suggests that the protein suppresses inflammation. The physiologic role of the protein remains to be determined.Keywords
This publication has 74 references indexed in Scilit:
- Human Uteroglobin Gene: Structure, Subchromosomal Localization, and PolymorphismDNA and Cell Biology, 1997
- Structural Basis for Calcium Binding by UteroglobinsJournal of Molecular Biology, 1996
- Plutonium-induced Proliferative Lesions and Pulmonary Epithelial Neoplasms in the Rat: Immunohistochemical and Ultrastructural Evidence for Their Origin from Type II PneumocytesVeterinary Pathology, 1994
- Refined structure of rat Clara cell 17 kDa protein at 3·0 Å resolutionJournal of Molecular Biology, 1992
- Clara cell 10 kDa protein (CC10): Comparison of structure and function to uterogloblinBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1990
- Uteroglobin inhibits phospholipase A2 activityLife Sciences, 1986
- X-ray crystallographic analysis of a progesterone-binding protein. The C2221 crystal form of oxidized uteroglobin at 2.2 Å resolutionJournal of Molecular Biology, 1980
- Ultrastructure of the Nonciliated Bronchiolar Epithelial (Clara) Cell of Mammalian Lung: II. A Comparison of Horse, Steer, Sheep, Dog, and CatExperimental Lung Research, 1980
- The formation of granules in the bronchiolar clara cells of the rat. II. Enzyme cytochemistryJournal of Ultrastructure Research, 1975
- The formation of granules in the bronchiolar Clara cells of the rat: 1. Electron microscopyJournal of Ultrastructure Research, 1974