VACUOLATION IN THE HUMAN CEREBRAL CORTEX AND ITS RELATIONSHIP TO THE INTERVAL BETWEEN DEATH AND AUTOPSY AND TO SYNAPSE NUMBERS: AN ELECTRONMICROSCOPIC STUDY
- 1 January 1979
- journal article
- research article
- Published by Wiley in Neuropathology and Applied Neurobiology
- Vol. 5 (1) , 1-7
- https://doi.org/10.1111/j.1365-2990.1979.tb00608.x
Abstract
Vacuolation in the human cerebral cortex resulting from swelling of cell processes after death was measured in electron micrographs in material obtained up to 69 h post mortem from subjects with no known neurological abnormality. Vacuolation increased significantly up to 30-35 h after death and then to decrease. Accompanying this change was a significant reduction in the numbers of recognizable synapses which probably resulted from compression due to the vacuolation rather than from post-mortem disintegration.This publication has 3 references indexed in Scilit:
- Senile changes in the human neocortex and hippocampus compared by the use of the electron and light microscopesJournal of the Neurological Sciences, 1976
- A quantitative electron microscopic study of the ageing human cerebral cortexActa Neuropathologica, 1976
- THE DENSITY OF SYNAPSES AND NEURONS IN NORMAL, MENTALLY DEFECTIVE AND AGEING HUMAN BRAINSBrain, 1975