Abstract
The rate of uptake of Ca45 from the water in which they swim is greater for wild than lordotic guppies when the water contains 23 to 75 ppm Ca. When the water contains 275 ppm Ca, this difference is no longer apparent. The uptake of Sr90 is the same for both strains of fish and the uptake is not affected by the mineral content of the water. The incorporation of Ca45 by the spine is greater for the lordotic than the wild strain when Ca45 is taken up from tap water of low salt content, but the difference disappears when the water contains 275 ppm Ca. The incorporation of Sr90 by the spine for both strains is the same and is not affected by the mineral content of the water. These data indicate that the lordotic mutation in guppies is associated with a specific alteration in Ca metabolism.

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