2,2′-Spirobi(1,3,2-benzodioxaphosphole) : an inexpensive and effective reagent for peptide synthesis

Abstract
The Readily accessible spirocyclic oxyphosphorane, 2,2′-spirobi(1,3,2-benzodioxaphosphole)(1), is a convenient and effective reagent for peptide coupling, racemisation as measured by the lzumiya test being strikingly suppressed to N-hydroxysuccinimide.

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