An assessment of the Mi-Mark endoemtrial sampling technique.

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Abstract
Cytological smears (120) and 106 histological specimens were obtained from 115 patients using a new technique of endometrial sampling. It was an atraumatic procedure and was well-accepted by the patients. Some problems were encountered in the preparation of satisfactory cytological specimens and in their interpretation. The method was not completely reliable for detecting endometrial pathology and is therefore considered unsuitable for monitoring patients on hormone replacement therapy [administered for menopausal symptoms and suspected by causing cancer]. It was useful as a gynecological outpatient technique for sampling the endometrium when formal curettage was unsuccessful, in avoiding the necessity for a preoperative curettage to confirm suspected carcinoma, and in the investigation of infertility.