ON THE ORIGIN OF MACROPHAGE HETEROGENEITY - A HYPOTHESIS

  • 1 January 1983
    • journal article
    • research article
    • Vol. 33  (3) , 207-220
Abstract
An inherent heterogeneity of bone marrow macrophage precursor cells was suggested. The possible relationship of this heterogeneity with the functional heterogeneity of blood monocytes and tissue macrophages under normal conditions and at an inflammatory site is discussed. A hypothesis suggesting that the bone marrow compartment is involved in the generation of macrophage heterogeneity is presented.