Crystal Structures of Penicillin-binding Protein 2 from Penicillin-susceptible and -resistant Strains of Neisseria gonorrhoeae Reveal an Unexpectedly Subtle Mechanism for Antibiotic Resistance
Open Access
- 1 January 2009
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 284 (2) , 1202-1212
- https://doi.org/10.1074/jbc.m805761200
Abstract
No abstract availableThis publication has 76 references indexed in Scilit:
- Crystal Structures of Biapenem and Tebipenem Complexed with Penicillin-Binding Proteins 2X and 1A from Streptococcus pneumoniaeAntimicrobial Agents and Chemotherapy, 2008
- Diversity of penA Alterations and Subtypes in Neisseria gonorrhoeae Strains from Sydney, Australia, That Are Less Susceptible to CeftriaxoneAntimicrobial Agents and Chemotherapy, 2007
- Neisseria gonorrhoeae Isolates with Reduced Susceptibility to Cefixime and Ceftriaxone: Association with Genetic Polymorphisms in penA , mtrR , porB1b , and ponAAntimicrobial Agents and Chemotherapy, 2007
- Amino Acid Substitutions in Mosaic Penicillin-Binding Protein 2 Associated with Reduced Susceptibility to Cefixime in Clinical Isolates of Neisseria gonorrhoeaeAntimicrobial Agents and Chemotherapy, 2006
- Crystal Structure of Penicillin-binding Protein 1a (PBP1a) Reveals a Mutational Hotspot Implicated in β-Lactam Resistance in Streptococcus pneumoniaeJournal of Molecular Biology, 2006
- The crystal structure of the penicillin-binding protein 2x from Streptococcus pneumoniae and its acyl-enzyme form: implication in drug resistance 1 1Edited by R. HuberJournal of Molecular Biology, 2000
- Refinement of Macromolecular Structures by the Maximum-Likelihood MethodActa Crystallographica Section D-Biological Crystallography, 1997
- [20] Processing of X-ray diffraction data collected in oscillation modePublished by Elsevier ,1997
- The CCP4 suite: programs for protein crystallographyActa Crystallographica Section D-Biological Crystallography, 1994
- Hybrid penicillin-binding proteins in penicillin-resistant strains of Neisseria gonorrhoeaeNature, 1988