Thematic review series: Lipid Posttranslational Modifications. Fighting parasitic disease by blocking protein farnesylation
Open Access
- 1 February 2006
- journal article
- review article
- Published by Elsevier in Journal of Lipid Research
- Vol. 47 (2) , 233-240
- https://doi.org/10.1194/jlr.r500016-jlr200
Abstract
No abstract availableKeywords
This publication has 65 references indexed in Scilit:
- Phase I Study of the Farnesyltransferase Inhibitor BMS-214662 Given Weekly in Patients with Solid TumorsClinical Cancer Research, 2005
- Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitorsCancer Cell, 2005
- PostprenylationCAAXProcessing Is Required for Proper Localization of Ras but Not Rho GTPasesMolecular Biology of the Cell, 2005
- Farnesyltransferase inhibitor BMS-214662 induces apoptosis in B-cell chronic lymphocytic leukemia cellsLeukemia, 2004
- Crystallographic Analysis of CaaX Prenyltransferases Complexed with Substrates Defines Rules of Protein Substrate SelectivityJournal of Molecular Biology, 2004
- Blocked Pathways: FTIs Shut Down Oncogene SignalsThe Oncologist, 2003
- High Affinity for Farnesyltransferase and Alternative Prenylation Contribute Individually to K-Ras4B Resistance to Farnesyltransferase InhibitorsJournal of Biological Chemistry, 2003
- Trypanosoma brucei prenylated-protein carboxyl methyltransferase prefers farnesylated substratesBiochemical Journal, 2002
- Farnesylated proteins and cell cycle progressionJournal of Cellular Biochemistry, 2001
- Inhibitors of the Nonmevalonate Pathway of Isoprenoid Biosynthesis as Antimalarial DrugsScience, 1999