QUALITY-CONTROL OF AGAR DIFFUSION SUSCEPTIBILITY TESTS - DATA FROM THE QUALITY ASSURANCE SERVICE MICROBIOLOGY PROGRAM OF THE COLLEGE-OF-AMERICAN-PATHOLOGISTS

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  • 1 January 1980
    • journal article
    • research article
    • Vol. 74  (4) , 581-585
Abstract
From 1974 through Dec. 1978, over 180 laboratories participated in the Microbiology Program of the College of American Pathologists Quality Assurance Service (QAS), submitting 2,372,000 individual antibiotic determinations on 3 quality control reference strains [Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa]. Of these determinations, 89.5% were obtained by the standard Bauer-Kirby method; 8.4% by the agar overlay modification of Barry and associates. Standard statistical analysis of data obtained using the agar overlay modification was reported for each antimicrobic/reference strain combination. Comparisons were made between the QAS data and data obtained in earlier collaborative studies, which currently serve as precision and accuracy control limits. In many cases, QAS data exceed the existing control limits.

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