Chiral Sulfonamide Induced Enantioselective Protonation of Samarium Enolate in the Reaction of α,β-Unsaturated Ester with Ketone
- 31 October 2000
- journal article
- research article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 2 (24) , 3773-3776
- https://doi.org/10.1021/ol006429c
Abstract
Good enantioselectivity (up to 84% ee) has been achieved in the formation of α,γ-substituted-γ-butyrolactone by the SmI2-mediated reductive coupling of ketones with methyl methacrylate using various chiral proton sources.Keywords
This publication has 1 reference indexed in Scilit:
- SmI2-induced reductive cross-coupling of carbonyl compounds with (α,β-unsaturated estersTetrahedron Letters, 1986