Review of current treatment practices for carcinoma of the head and neck
- 15 June 2005
- journal article
- review article
- Published by Informa Healthcare in Expert Opinion on Pharmacotherapy
- Vol. 6 (7) , 1143-1155
- https://doi.org/10.1517/14656566.6.7.1143
Abstract
The past two decades have witnessed a paradigm shift in the treatment of squamous cell carcinoma of the head and neck. Innovation in chemotherapy, radiotherapy and surgery has led to the assimilation of these modalities into our treatment algorithms. This modern multipart treatment plan has led to improved survival; however, this has come at the cost of increased toxicity. New and future therapies will be more tumour specific and, ideally, less toxic. Current research centres on these tumour-specific therapies with the anticipation of improved survival with decreased toxicity. This article will review the standard of care, recent advances and unfulfilled needs in the treatment of squamous cell carcinoma of the head and neck.Keywords
This publication has 73 references indexed in Scilit:
- Rationale and clinical basis for combining gefitinib (IRESSA, ZD1839) with radiation therapy for solid tumorsInternational Journal of Radiation Oncology*Biology*Physics, 2004
- Neck dissection in the combined‐modality therapy of patients with locoregionally advanced head and neck cancerHead & Neck, 2004
- Cancer Statistics, 2004CA: A Cancer Journal for Clinicians, 2004
- Intensity-Modulated RadiotherapyThe Cancer Journal, 2002
- ZD1839 (???Iressa???)*,??? as an Anticancer AgentDrugs, 2000
- Head and Neck CancerDrugs, 1996
- Head and Neck CancerNew England Journal of Medicine, 1993
- Analysis of gene amplification in head‐and‐neck squamous‐cell carcinomasInternational Journal of Cancer, 1991
- Induction Chemotherapy plus Radiation Compared with Surgery plus Radiation in Patients with Advanced Laryngeal CancerNew England Journal of Medicine, 1991
- Treatment of choice for squamous carcinoma of the tonsillar fossaHead & Neck Surgery, 1985