3-Amino-4-thiocarbamoyl-3-pyrrolines: their conversion into pyrrolo[3,4-d]pyrimidine-4-thiols
- 1 January 1967
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society C: Organic
- p. 698-701
- https://doi.org/10.1039/j39670000698
Abstract
The ready preparation of 3-amino-1,2,2-trimethyl-4-thiocarbamoyl-3-pyrroline by the action of thioacetamide on the corresponding 3-amino-4-cyanopyrroline is described. This is treated with triethyl orthoformate, acid chlorides, and thioacetamide to give the corresponding dihydropyrrolo[3,4-d]pyrimidine-4-thiols which are S- alkylated.Keywords
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