Adjuvant Properties of Retinol on IgE Production in Mice
- 1 January 1979
- journal article
- research article
- Published by S. Karger AG in International Archives of Allergy and Immunology
- Vol. 59 (1) , 69-74
- https://doi.org/10.1159/000232241
Abstract
Mice treated with varying doses of retinol in Tween 80 showed no primary IgE response to ovalbumin in saline; however, reimmunization with ovalbumin in saline produced high IgE titers. Retinol-treated mice immunized with ovalbumin absorbed to Al(OH)3 also showed no primary IgE response, but high secondary responses. Significantly, animals treated with Tween 80 only prior to immunization with ovalbumin adsorbed to Al(OH)3 also demonstrated no primary IgE response, indicating that Tween 80 inhibited the primary IgE response.This publication has 3 references indexed in Scilit:
- Antibody synthesis stimulation by vitamin A in chickensBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1977
- Listeria Cell Wall Fraction: A B Cell AdjuvantThe Journal of Immunology, 1976
- Adjuvanticity of Vitamin ANature, 1968