SPACE-FLIGHT EFFECTS ON SKELETAL-MUSCLES OF RATS

1 January 1976

journal article
research article

Vol. 47 (7) , 700-703

Abstract

Morphological and histochemical examinations of the skeletal muscles of rats flown for 22 days aboard the Cosmos-605 biosatellite have demonstrated atrophic and dystrophic developments in the soleus muscle accompanied by metabolic changes in the muscle tissue. The changes were reversible but did not disappear entirely 27 days postflight. Early atrophic developments were seen in the gastrocnemius, quadriceps and extensor digitorum longus muscles on the 2nd postflight day. The comparative study of the muscles of flight and simulation rats has shown that pathology developed in the muscles as a result of diminished motor activity of animals being aggravated by weightlessness.

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