Serum-Ionized Calcium as a Diagnostic Tool in Hypercalciuria

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Abstract
Serum-ionized calcium (Ca++) was measured in 65 patients with idiopathic calcium urolithiasis. The patients were then divided into hypercalciuric and normocalciuric groups based on the mean + SD of the control group, with greater than 180 mg/24 h in males and greater than 176 mg/24 h in females defined as hypercalciuria. The results showed a decrease in the tubular reabsorption of calcium in the hypercalciuric group, but not in the normocalciuric group. The hypercalciuric group was then further divided into group I with increased filtered load and group II with normal filtered load. It was suggested that the group I hypercalciurics had absorptive hypercalciuria and group II renal hypercalciuria.

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