OXYGEN CONSUMPTION AND BLOOD FLOW IN THE SUBMAXILLARY GLAND OF THE DOG

Publisher Website
Google Scholar
Abstract
The blood flow and oxygen consumption of the submaxillary glands of seven dogs were measured while the glands were at rest and during secretory activity. Serial samples of blood were delivered directly from blood vessels to the cell of a cuvette oximeter, so that during the course of an experiment changes in haemoglobin concentration and oxygen saturation of the blood issuing from the submaxillary vein could be followed. A. flowmeter connected with the salivary duct, and recording on a Sanborn Polyviso, gave a continuous record of the rate of saliva flow. The resting blood flow was 0.26 ± 0.11 ml/g min and the resting oxygen consumption, 27 ± 6 μl/g min. During activity there was an approximately linear relationship between the rate of saliva flow and the the extra oxygen consumption. There was poor correlation between oxygen consumption and blood flow. Atropine had little or no effect on resting glands, but depressed both the rate of saliva flow and the extra oxygen consumption associated with it, in doses which had no effect on the vasodilator response to stimulation.