Abstract
Best response to thiamine in deficient rats at an environmental temp, of 91[degree]F was obtained at dietary thiamine cones, twice as high as were needed to give an optimal response at 65[degree]F. Rats at 65[degree]F ate twice as much food as at 91 [degree]F, and actual thiamine intakes were about the same for optimal response at the two temp. levels. Further supplemental adm. of thiamine served to protect rats against more excessive heat (95-96[degree]). The bearing of this higher thiamine requirement per g. of food at high environmental temps, is discussed in rela-tion to tropical malnutrition and to the prevalence of vit. deficiency diseases in tropical and sub-tropical regions.

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