2, 3-Diphosphoglycerate and Phosphoglycerate Mutase Levels in Animal Tissues and Erythrocytes

Abstract
A direct method for simultaneously estimating the activity of phosphoglycerate mutase [EC 2.7.5.3] and the concentration of 2,3-diphosphoglycerate in tissue homogenates and in the hemolysates of mammals was established. By this method, a marked increase in the activity of phosphoglycerate mutase was observed in the red cells of patients with anemia and congestive heart failure, while the concentration of 2, 3-diphosphoglycerate was in the normal range.

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