Isolation and Structure of Bacterial Sex Pheromone, cPD1
- 16 November 1984
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 226 (4676) , 849-850
- https://doi.org/10.1126/science.6436978
Abstract
The Streptococcus faecalis sex pheromone cPD1, which induces a mating response in cells harboring the conjugative plasmid pPD1, has been isolated and its structure determined. It was found to have a molecular weight of 912, and its amino acid sequence was H-Phe-Leu-Val-Met-Phe-Leu-Ser-Gly-OH. A synthetic octapeptide showed the same biological activity and chromatographic behavior as the isolated cPD1. Pheromone activity was detectable at a concentration of approximately 4 × 10 -11 M .This publication has 16 references indexed in Scilit:
- Structures of tremerogens A-9291-I and A-9291-VIII: peptidal sex hormones of Tremella brasiliensisBiochemistry, 1984
- Plasmids, drug resistance, and gene transfer in the genus StreptococcusMicrobiological Reviews, 1981
- Peptidal Sex Hormones Inducing Conjugation Tube Formation in Compatible Mating-Type Cells of Tremella mesentericaScience, 1981
- New detection and separation method for amino acids by high-performance liquid chromatographyJournal of Chromatography A, 1981
- Sex pheromone cAD1 in Streptococcus faecalis: induction of a function related to plasmid transferJournal of Bacteriology, 1980
- Plasmid transfer in Streptococcus faecalis: Production of multiple sex pheromones by recipientsPlasmid, 1979
- Primary Structure of α‐Factor Peptides from Saccharomyces cerevisiaeEuropean Journal of Biochemistry, 1976
- Conjugal Transfer of Plasmid-Borne Multiple Antibiotic Resistance in Streptococcus faecalis var. zymogenesJournal of Bacteriology, 1974
- The use of N-hydroxy-5-norbornene-2,3-dicarboximide acitive esters in peptide synthesis.CHEMICAL & PHARMACEUTICAL BULLETIN, 1974
- Use of Anhydrous Hydrogen Fluoride in Peptide Synthesis. I. Behavior of Various Protective Groups in Anhydrous Hydrogen FluorideBulletin of the Chemical Society of Japan, 1967