The effect of intravenous adrenaline and noradrenaline infusion of peripheral lymph flow in the sheep.

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Abstract
Pressure fluctuations and lymph flow were measured in popliteal, prefemoral and mesenteric efferent lymphatic vessels in conscious sheep. Adrenaline [epinephrine] infusion i.v. increased frequency of lymphatic contraction and lymph flow in all 3 vessels. In the case of the prefemoral vessels, flow remained high after the infusion had stopped. Noradrenaline infusion i.v. increased frequency of contraction and lymph flow in all 3 vessels but prefemoral flow was depressed after the infusion had stopped. Lymphatic frequency of contraction and lymph flow increased when the animals were startled. Anesthetizing the animals with pentobarbitone did not abolish lymphatic contractors, nor did it prevent the response to adrenaline and noradrenaline [norepinephrine] infusions. Adrenaline and noradrenaline evidently act by increasing frequency and force of pumping of lymph vessels.

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