Antacid Relief of Diarrhea In Zollinger-Ellison Syndrome

Publisher Website
Google Scholar
Abstract
To the Editor:— A patient who presented with diarrhea, vague abdominal distress, and no demonstrable ulcer by x-ray film was lated found to have the Zollinger-Ellison syndrome. The empiric use of a magnesium-aluminum hydroxide suspension (Maalox) for relief of abdominal distress also relieved the diarrhea. This commonly used antacid combination of magnesium and aluminum hydroxide ordinarily exerts alaxativeeffect. The paradoxical antidiarrheal response to magnesiumaluminum hydroxide suspension offers a diagnostic clue to the Zollinger-Ellison syndrome. Report of a Case:— This 19-year-old male was seen in April 1968 with a tenmonth history of diarrhea of six watery stools a day, abdominal cramping, nausea, and 20-lb weight loss. An upper gastrointestinal tract series was normal, but clumping and segmentation of barium was present in the small bowel. Triolein I 131 absorption was diminished to 7%. Barium enema x-ray films, proctoscopic examination, and stool cultures and examinations for ova and parasites showed

This publication has 0 references indexed in Scilit: