New Method for Comparing the Activity of Local Anesthetics Used in Dentistry

1 September 1975

journal article
research article
Published by SAGE Publications in Journal of Dental Research

Vol. 54 (5) , 978-981
https://doi.org/10.1177/00220345750540053801

Abstract

A method using conscious rats was designed to determine, measure, and compare the local anesthetic property of agents used in dentistry. The technique involves a local anesthetic blockade of the mental and incisive nerves at the mental foramen and electrical stimulation proximal to the anesthetized region. This pharmacodynamic method is simple to perform and appropriate for the assessment of local anesthetics as used in clinical dentistry.

Keywords

This publication has 3 references indexed in Scilit:

Nerve and Nerve-Muscle Preparations (As Applied to Local Anesthetics)
Published by Springer Nature ,1971
Duration of Local Anesthesia
Annual Review of Pharmacology, 1969
THE TESTING OF LOCAL ANAESTHETICS
British Medical Bulletin, 1946