In vitro activity of naftifine, a new antifungal agent
Open Access
- 1 March 1981
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 19 (3) , 386-389
- https://doi.org/10.1128/aac.19.3.386
Abstract
Naftifine exhibits an interesting in vitro spectrum of activity against dermatophytes (38 strains; minimal inhibitory concentration [MIC] range 0.1 to 0.2 microgram/ml), aspergilli (6 strains; MIC range, 0.8 to 12.5 microgram/ml), Sporothrix schenckii (2 strains; MICs, 0.8 and 1.5 microgram/ml), and yeasts of the genus Candida (77 strains; MIC range, 1.5 to greater than 100 microgram/ml). Its degree of efficacy is unaffected by the organism density in the test medium, and it is primarily fungicidal against dermatophytes as well as yeasts. Its in vitro efficacy is pH dependent and rises with increasing pH values.This publication has 2 references indexed in Scilit:
- [Deep-freeze preservation of fungi in liquid nitrogen as a basis for standardized inocula].1978
- Antifungal agentsPublished by Springer Nature ,1978