Immunocytochemical detection of tumours of neuroectodermal origin.
Open Access
- 1 May 1988
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 41 (5) , 586-589
- https://doi.org/10.1136/jcp.41.5.586
Abstract
Immunocytochemical methods were applied to bone marrow aspirate and cerebrospinal fluid specimens to show cellular reactivity with the monoclonal antibody UJ13A, which recognises an antigen expressed by cells of neuroectodermal origin. The antigen remained stable after air drying and appropriate fixation. In five patients with various neuroectodermal tumours the diagnostic advantages of these techniques were clear; they can be performed even when only very small amounts of diagnostic material are available.This publication has 3 references indexed in Scilit:
- A rapid procedure, by collagenase treatment and cytocentrifugation, for the cytological evaluation of bone marrow biopsy specimensClinical and Laboratory Haematology, 1986
- The characterisation of monoclonal antibodies against haemopoietic cells: Comparison of an immunoperoxidase method with fluorescence activated cell sortingJournal of Immunological Methods, 1983
- Biological characterization and clinical applications of a monoclonal antibody recognizing an antigen restricted to neuroectodermal tissuesInternational Journal of Cancer, 1983