1. Whole and/or partial body radiation therapy given in single doses has shown beneficial effects in the control of certain advanced cancers. The palliative effects compare favorably with results using anticancer drugs as commonly reported in the medical literature. Irradiation certainly seems to improve survival in the untreated patient with cancers of colon, lung and breast. 2. The use of autologous marrow reinfusion immediately after radiation therapy minimizes the characteristic marrow depression otherwise observed. The degree of illness following infusion is greatly lessened and hospitalization greatly shortened.