Parallel kinetic resolution of racemic amines using 3-N,N-diacylaminoquinazolin-4(3H)-ones
- 4 December 2001
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 24,p. 2684-2685
- https://doi.org/10.1039/b109297a
Abstract
The two pseudoenantiotopic N-acyl groups of enantiopure 3-[N-(3-m-acetoxyphenylpropanoyl)-N-(3-phenylpr opanoyl)amine]-2-isopropylquinazolin-4(3H)-one 7 each react with a different enantiomer of 2-methylpiperidine giving rise to efficient parallel kinetic resolution (ee > 95%).Keywords
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