Endotoxic Activity of L-Forms Derived from Salmonella paratyphi B.
- 1 November 1962
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 111 (2) , 399-400
- https://doi.org/10.3181/00379727-111-27804
Abstract
L-forms of Salmonella paratyphi B 777 were prepared in penicillin and maintained for several subcultures with and without the antibiotic. The toxicity of these L-forms was compared with the toxicity of parent bacterial cultures by intravenous injection into mice which had previously been infected with BCG and these were highly sensitive to endotoxin shock. L-forms were found to be 5.5 to 9 times less toxic than bacterial forms. The residual toxicity of L-forms remained constant during up to 6 subcultures in medium with or without penicillin.Keywords
This publication has 0 references indexed in Scilit: